CUTEHeart - Comparative use of technologies for coronary heart disease

  • Main research unit: Centro de Investigação em Tecnologias e Sistemas de Informação em Saúde (CINTESIS/FMUP)
  • Principal Investigator:  Este endereço de email está protegido contra piratas. Necessita ativar o JavaScript para o visualizar.
  • Team:
    • Almeida, Filipa
    • Azevedo, Luís Filipe
    • Azzone, Vanessa
    • Fahad, Al Sidi
    • Freitas, Alberto
    • Melica, Bruno
    • Normand, Sharon-Lise
    • Pereira-Miguel, José
    • Resnic, Frederic
    • Rocha-Gonçalves, Francisco
    • Soares, António José
    • Teixeira-Pinto, Armando
  • Fellows
    • Lobo, Mariana
  • Financing: € 333,327.00 (FCT)
  •  Start date: 15.05.2012 | End date: 15.05.2015

Project description:

Different health systems have different abilities to adopt health technologies. These differences may me even more apparent among countries with contrasting gross domestic products, state-based vs. private-based health systems, scientific and professional development levels, and population epidemiological profiles. Nonetheless, whenever new technology is determined to be cost-effective compared to previous available care, there may be significant individual and societal benefits to its adoption and access independent of health system. The accurate determination of whether technologies are both clinically effective and cost-effective is thus of critical importance. The overall intent of most effectiveness measures is to provide an opportunity to improve the value of healthcare delivery by eliminating waste and possibly reducing costs where they are not justified. By merging data on clinical efficacy with cost to provide estimates of cost-effectiveness, health technology assessment (HTA) can be utilized to help generate evidence-based guidelines that support decision to utilize new technologies. The accurate evaluation of health technology requires an understanding of local disease epidemiology, institutional resources, specialized professional training, and clear political planning, surveillance, and evaluation instruments.

The goal of this study will be to compare the use of health technologies between the health systems, of the United States and Portugal, with a focus on the treatment of coronary heart disease (CHD). CHD apart from being highly prevalent and a major cause of death in Western countries, is also a leading problem because of the high economic burden it imparts on health systems. The economic cost of CHD relates not only to the direct cost to the healthcare system but also to loss of productivity, and to the provision of formal and informal patient care. However, current estimates of cost are limited to certain populations for whom this data is available (such as the Medicare population), and few have successfully compared CHD-attributable costs across distinct populations and health systems. We will empirically compare the use of technologies to treat coronary heart disease, the impact of selected CHD treatments on outcomes between two health care systems, and the associated costs. Our long-term goal is to develop a program of health services research, beyond CHD, that exploits similarities and differences between the US and Portuguese health care systems. We will achieve these goals through four specific aims. Aim 1 involves a comparison of the utilization and diffusion rates of new technologies for diagnosing and treating CHD between the US and Portugal. This will permit characterization of the pattern of the cumulative percentage of hospitals that adopt a new technology over time, decompose the variations in the use of CHD treatments as a function of patient, hospital, and health system characteristics and comparison these associations between the two countries. This will permit identification of facts impacting utilization at the individual admission level. Aim 2, assesses the impact of health technology diffusion in High Risk Patient Cohorts. Aim 3 estimates the comparative effectiveness of CHD treatments. Aim 4 estimates the cost-effectiveness of CHD treatments. Aim 5 builds a framework for design and implementing comparative health services research between two health care systems.

Website: soon available

Code: HMSP-ICT/0013/2011


Main research unit: Unidade de Estudos Avançados de Energia do Ambiente Construído (IDMEC Porto/FE/UP)

Principal Investigator: André Miguel Afonso de Sousa Moreira


  • Ana Ferreira
  • Ana Mendes
  • Anabela Martins
  • C. Pereira
  • Eduardo Fernandes
  • Gabriela Ventura Alves da Silva
  • Isabella Annesi-Maesano
  • Joana Madureira
  • João P. Teixeira
  • José Alexandre
  • José Delgado
  • Klára Slezáková
  • Maria Pereira
  • Susana Daniela da Silva Martins
  • José Henrique Dias Pinto de Barros

Financing: € 197.906,00 (FCT)

Project description: Children spend most of their time indoors, basically at home or school. Scientific evidence has shown that exposure to indoor air pollution can cause or contribute to short and long-term health problems including asthma and respiratory tract infections. Nevertheless, although the considerable interest in recent years of the health effects of indoor air pollution, issues such as specific home and school environments determinants associated with the burden of these diseases remain poorly know. We aimed to assess and understand risk factors for children's health in relation with exposure to indoor air in schools, taking into account also the contribution of the home environment. Specifically, the project aims: to investigate the role of the indoor environment in schools and homes for children's health; and to identify technical solutions which safeguard the health of children in schools.

The team members of this project intend to study the exposure of children to indoor air in 20 public primary schools and investigate the associated respiratory and allergic related health effects in 1600 children's. From these, a randomized sample of children's will perform more accurate clinical tests and biomarkers. A case-control study will then be implemented, where emphasis will be put on the survey of the buildings of the households and of the families' behavior in order to investigate their potential relationship with the eventual allergic and respiratory symptoms. An intervention study was also planned in order study the effectiveness of interventions in order to improve the IAQ and the safeguard of schoolchildren's.

This work aims at to go as in depth as possible to gather more and new data in order to enhance the existing information on children exposure to indoor air. The study shall also provide useful data for undertaking risk assessment and risk management related to exposure to indoor air pollution and will allow for better define public health policies and prevention strategies, good practices regarding building design, construction and management as well as on maintenance and day-by-day use.

To reach the above with success it is essential to count on a specific institutional and scientific environment such as the one provided by the University of Porto through Faculty of Medicine, Faculty of Engineering, Institute of Mechanical Engineering and Institute of Public Health. In a context of an interdisciplinary research team made of medical doctors and other health professionals, environment specialists and mechanical engineers, all the conditions seem to be created to make this work possible and poised for success.

The project will have two consultants. One in France, head of the Occupation and Epidemiology Assembly at the European Respiratory Society; and one Portuguese where both will have a relevant role in health related tasks.


Adaptive Learning Systems II

  • Principal Investigator: João Manuel Portela Gama
  • CINTESIS/FMUP contact:  Este endereço de email está protegido contra piratas. Necessita ativar o JavaScript para o visualizar.
  • Project at FCT - (POSC/EIA/55340/2004



AB+K- Use of Information Technologies for the Rational Prescription of Antimicrobials in Intensive Care Medicine

Principal Investigator: António Megre Sarmento


Análise Automatizada do Cardiotocograma na Gravidez Gemelar: Desenvolvimento e Avaliação

  • Principal Investigator: João Francisco Lima Bernardes 
  • CINTESIS/FMUP contact: Este endereço de email está protegido contra piratas. Necessita ativar o JavaScript para o visualizar.
  • PBIC/CEG/2443/95



Secção Ensino Secção investigacao Secção consultadoria
   Mestrados | Doutoramentos | Formação Contínua         Projetos | Teses e Dissertações | Publicações        Bioestatística | Informática Médica